by Beonchip | Oct 14, 2025 | Be-Flow, Chips, Organ on a chip, Technical Notes
Summary Reproducing the vascular microenvironment in vitro requires not only dynamic culture systems, such as microfluidic organ-on-chip devices, but also the appropriate extracellular matrix (ECM) coating. Laminins, key components of the basal lamina, provide...
by Beonchip | Jun 2, 2025 | Be-Doubleflow, Chips, Organ on a chip, Technical Notes
Introduction The intestine harbors a commensal microbiome that plays a crucial role in its physiology and functionality. Notably, some of the microorganisms residing in the intestine require anaerobic conditions to survive. [1] For the small intestine, oxygen levels...
by Beonchip | Apr 22, 2022 | Be-Doubleflow, Chips, Organ on a chip
This technical note focuses on the development of a 3D model using GrowDex®-T in a Be-Doubleflow chip under active flow. Introduction Rapidly evolving fields of medicine and pharmaceutics require more robust, cost-effective, ethical, and complex systems to better...
by Beonchip | Feb 23, 2022 | Be-Flow, Chips, Organ on a chip
Introduction Gut-on-a-chip models offer a powerful in vitro platform for studying the physiology and patho-physiology of the intestine. The gut is home to a microbiome that plays an important role in health and disease. Hypoxic conditions in the intestine allow...
by Beonchip | Aug 15, 2021 | Organ on a chip
Understanding the importance of shear stress in biology is essential for unraveling how mechanical forces influence cellular behavior, tissue development, and disease progression. For example, up to 60% of the human adult body is water. This water is stored both...
by Beonchip | Apr 13, 2021 | Organ on a chip
Introduction In vitro cell culture platforms are essential for modern research, clinical studies, and drug development. For more than a century, the petri dish has been the cornerstone of in vitro cell culture. The inventor of this technology, Julius Richard Petri,...
