Be-Doubleflow Custom

Name: Be-Doubleflow Custom
SKU: 1002-1
Availability: InStock

€ 550,0

The Be-Doubleflow is one of our most popular and adaptable microfluidic chips—engineered to support high-performance research in co-culture systems, barrier models, and dynamic microenvironments.

With two parallel microchannels separated by a porous PET membrane, it allows precise and dynamic crosstalk between compartments—ideal for simulating physiological and pathological conditions under continuous flow.

Dual-Channel Precision for Advanced Co-Culture Studies

Co-Culture: 2D and 3D interaction under controlled flow.
Barrier Models: Endothelial or epithelial barriers with shear stress on both sides (gut-on-chip, BBB-on-chip, liver-on-chip, kidney-on-chip and more)
Gas Control: Create hypoxic, anaerobic, or ischemia–reperfusion conditions.
Circulating Cells: Study immune cells, bacteria, or CTCs under flow.
Migration & Invasion: Track cell movement across the membrane in real time.
Drug Testing: Analyze permeability and transport across tissue interfaces.

Gas-Controlled Microenvironments

Beyond its versatility, the Be-Doubleflow stands out for its gas control capability. Thanks to its material composition, it supports the creation of hypoxic, anaerobic, and ischemia–reperfusion environments—perfect for mimicking complex in vivo conditions in a reproducible and controlled manner.

Customizable to Fit Your Research

The Be-Doubleflow is widely customizable—available with tailored channel dimensions, membrane pore sizes, and alternative materials. Choose your best combination.

Our team provides comprehensive design support to adapt the device to your specific workflow.

For quality optimization reasons, chips with channel height of 570 µm are not compatible with channel widths of 2.5 mm and above.

Channel dimensions width

Upper channel height

Lower channel height

Pore size

Base

Clear

· 10 devices per box

· For special requests. Contact >

· Would you like to see more information culture models, applications, video tutorials or downloading the PDF user guide of the Be-Doubleflow.

Go to the Be-Doubleflow information section >

Be-Doubleflow Custom

€ 550,0

The Be-Doubleflow is one of our most popular and adaptable microfluidic chips—engineered to support high-performance research in co-culture systems, barrier models, and dynamic microenvironments.

With two parallel microchannels separated by a porous PET membrane, it allows precise and dynamic crosstalk between compartments—ideal for simulating physiological and pathological conditions under continuous flow.

Dual-Channel Precision for Advanced Co-Culture Studies

Co-Culture: 2D and 3D interaction under controlled flow.
Barrier Models: Endothelial or epithelial barriers with shear stress on both sides (gut-on-chip, BBB-on-chip, liver-on-chip, kidney-on-chip and more)
Gas Control: Create hypoxic, anaerobic, or ischemia–reperfusion conditions.
Circulating Cells: Study immune cells, bacteria, or CTCs under flow.
Migration & Invasion: Track cell movement across the membrane in real time.
Drug Testing: Analyze permeability and transport across tissue interfaces.

Gas-Controlled Microenvironments

Beyond its versatility, the Be-Doubleflow stands out for its gas control capability. Thanks to its material composition, it supports the creation of hypoxic, anaerobic, and ischemia–reperfusion environments—perfect for mimicking complex in vivo conditions in a reproducible and controlled manner.

Customizable to Fit Your Research

The Be-Doubleflow is widely customizable—available with tailored channel dimensions, membrane pore sizes, and alternative materials. Choose your best combination.

Our team provides comprehensive design support to adapt the device to your specific workflow.

For quality optimization reasons, chips with channel height of 570 µm are not compatible with channel widths of 2.5 mm and above.

Channel dimensions width

Upper channel height

Lower channel height

Pore size

Base

Clear

· 10 devices per box

· Contact us for special requests

· For more information please Download the Technical PDF

Worldwide commercial network

We ship our products worldwide working with the best carriers.

Delivery time

Fast and efficient delivery times.

After-sales support

Live communication for assist you throughout all the process.

Worldwide commercial network

We ship our products worldwide working with the best carriers.

Delivery time

Fast and efficient delivery times.

After-sales support

Live communication for assist you throughout all the process.

Worldwide commercial network

We ship our products worldwide working with the best carriers.

Delivery time

Fast and efficient delivery times.

After-sales support

Live communication for assist you throughout all the process.

Be-Doubleflow information

Download the Technical PDF

Explore the crosstalk in the endothelium epithelium barrier under flow in both channels of the device, mimicking a more physiological environment for the study of different organs such as kidney, liver, gut or heart, among others.

Combine 3D and 2D cultures in a hypoxia environment where oxygen is supplied to the cells via the medium flowing in one of the channels.

Research the effect of circulating particles such as circulating tumor cells, immune system cells, bacteria, fungi, viruses and many more in a single cell culture, or in a complex coculture.

This device comprises two fluidic channels separated by a porous membrane that facilitates interaction between one channel and another while serving as a platform for the culture of different cell types. Some applications with this device include:

Epithelial/endothelial barrier models where shear stress plays a relevant role: lung, gut, kidney, liver, eye.
Gas control for anaerobic and hypoxic environments in the chip, adapting to changes in cell culture conditions and precise nutrient supply through perfused media. For example, creating an optimal environment for intestinal microbiota growth.
Muscle models: Co-culture of muscle layer with vasculature subjected to relevant shear stress.
Co-cultivation in both 2D and 3D
Unfolding organoids onto the porous membrane.
Invasion, cell migration, and metastasis processes between compartments by selecting the appropriate pore size.
Circulating particle assays involving immune system cells, vesicles, nanoparticles, encapsulated drugs, circulating tumor cells, bacteria, virus, under blood flow conditions.
Rolling and adhesion assays to study the ability of cells like leukocytes to adhere and roll on an endothelial surface, allowing for the final process of diapedesis and transmigration.