DIAMOOC Project: Integrated AI Design and Engineering of 3D Bioprinted Multi-Organoids on Chip for Tumor Diagnosis and Therapy
The project aims to develop an innovative colorectal cancer model that integrates a large bioprinted colorectal cancer organoid. This organoid will be combined with the vascular system that nurtures it inside a microfluidic chip. This groundbreaking model will have significant applications in pharmaceutical research and biomedicine. It will also pave the way for the application of in vitro models in personalized medicine, starting where it is most needed—oncology.
The general objective of DIAMOOC is to generate a robust in vitro platform for evaluating drugs used in colorectal cancer treatment. This platform addresses key drawbacks of patient-derived organoid research. Specifically, it overcomes the lack of a vascular network and immune system activity in the organoid microenvironment.
To accomplish this objective, DIAMOOC integrates various fields of research, forming a multidisciplinary consortium. It combines expertise in machine learning, artificial intelligence, bioprinting, biological simulation, microfluidic engineering, and biomedicine.
Beonchip will play a critical role in the DIAMOOC project. It will be responsible for designing and fabricating microfluidic platforms compatible with bioprinting for the culture of large organoids on a chip.
This project is part of the CHINEKA Spanish-Chinese Bilateral Technological Cooperation Program. This program is a collaboration between the CDTI and TORCH. CHINEKA supports the joint development of technological innovation projects between Spanish companies and Chinese entities, with funding provided by both countries.
DIAMOOC consortium is integrated by BEONCHIP S.L. (Spain), University of Zaragoza (Spain), Nanjing Tech University (China) and Chengdu MatAi Technology Co., Ltd. (China)
Project reference: CHK-20210004